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  Indian J Med Microbiol
 

Figure 1: Myeloid precursors fail to differentiate under the effect of the growing myeloma cells with the accumulation of immature myeloid-derived suppressor cells. Furthermore, Macrophages are polarized to M2 favoring tumor growth and dendritic cells engulfing apoptotic plasma cells have an impaired antigen expression potential. Myeloid-derived suppressor cells also favor the transition of T cells to T-regulatory cells

Figure 1: Myeloid precursors fail to differentiate under the effect of the growing myeloma cells with the accumulation of immature myeloid-derived suppressor cells. Furthermore, Macrophages are polarized to M2 favoring tumor growth and dendritic cells engulfing apoptotic plasma cells have an impaired antigen expression potential. Myeloid-derived suppressor cells also favor the transition of T cells to T-regulatory cells